Computational Biology
Abstract artistic representation of alkaline hydrothermal vents with spiraling geological formations

The Drive to Life on Wet and Icy Worlds

A reformulated theory for the origin of life focusing on alkaline hydrothermal vents as electrochemical reactors.

Computational Biology
Electron microscope image of Pyrolobus fumarii showing irregular coccoid cell structure

Three Domains of Life: Woese's Phylogenetic Revolution

Woese et al.'s landmark 1990 paper established the three-domain system based on ribosomal RNA phylogeny, revolutionizing …

Computational Biology
A reconstruction of LUCA within its evolutionary and ecological context

The Nature of LUCA and Early Earth System

Phylogenomic reconstruction of LUCA revealing a complex, 4.2 Ga old acetogen living in an established ecosystem.